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Combinatorial Chemistry

Combinatorial Chemistry Certification Training


Program/Course ID:COMCH
Enrollment Period:12 months.
Average Learning Time:~.
Additional Resources:Supplemental materials/activities.
Credit Hours:3 credits.
Method of Training:
Online, asynchronous, self-paced eLearning.
Accessibility:24/7 access to all program materials.
Demonstration:Four (4) free trial courses are available.
Group/Employee Training: Click here to request a quote.
Final Assessment:Multiple choice; unlimited attempts.
Certificate:Encrypted PDF with validation QR barcode.

2024 UPDATE:
This program is currently unavailable for enrollment.

It may have been updated or discontinued.
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Outline:


INTRODUCTION
1. Course Information
2. Interface Tour
3. Course Overview

COMBICHEM OVERVIEW
2. Objectives
3. Medicinal Chemistry
4. Combinatorial Chemistry
5. High-Throughput Screening
6. HTS Assays
7. uHTS Requirements
8. Progress Check

DIVERSITY ANALYSIS
9. Objectives
10. Selection and Diversity
11. Peptide Libraries
12. DNA Shuffling
13. Strategic Options
14. Molecular Diversity
15. Synthesis Strategies
16. Phage Display
17. Progress Check

LIBRARY DESIGN
18. Objectives
19. Drug Pharmacophores
20. Library Design
21. Lead Optimization
22. Applications
23. Progress Check

Objectives:


Define the two technologies that now allow the creation of large combinatorial libraries of compounds
List the three functions that combinatorial chemistry brings to synthetic medicinal chemistry
Describe the difference between the three different types of assays with which combinatorial libraries are usually tested
Specify two of the features of an assay that allow it to be amenable to high-throughput screening
Explain the advantages of HTRF-based assays
Describe the three principal requirements needed to scale an assay to the level of uHTS
Define the difference between a diverse library and a focused or biased library
Calculate the number of combinations of molecules capable of being created from an n-mer peptide library
List three classes of proteins that have been 'improved' using DNA shuffling
Specify the strategic options available in the creation of a combinatorial library
Describe how molecular diversity can be obtained in protein, peptide, nucleic-acid or small-molecule libraries
Define and explain the two major strategies for synthesizing small-molecule libraries
List the nine steps involved in creating antibodies via phage display
Understand the key features of a drug pharmacophore
List some of the parameters involved in designing combinatorial drug libraries
Define the two major parameters in drug optimization that can benefit from drug design
Give two examples of drugs that can now be synthesized by solid-phase combinatorial synthesis

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Benefits of Training with Biopharma Institute

Immediate access to courses:Username, password, instructions, and receipt of payment are immediately emailed upon online enrollment.
Self-paced, asynchronous eLearning:24/7 access to all course materials and assessments for 12 months.
Open enrollment:No prior course prerequisites or work experience required.
Expertise:Courses developed by subject matter experts (SMEs) in the area being taught.
Current and validated:Training is current with respect to regulations, procedures, and 3rd party validated and/or accredited.
Optimized for learning:Courses include voiceovers, easy navigation, reading materials, case studies, progress checks, and high-quality animations to increase retention of subject matter.
Secure and safe access:Encrypted website and LMS connections, firewall, and daily malware scans deliver optimal security and performance.
Flexible final assessments:Multiple-choice questions can be taken repeatedly until a passing score is achieved.
Direct access to certificates:Upon completion, certificates are immediately issued in an encrypted PDF format. Certificates include a watermark, unique validation code, and QR verification barcode.
Verification of training:Certificates are verifiable online using QR barcode or the unique ID code. Digital badges are additionally issued for all professional certification programs.
Training manager access:A proprietary portal offers access to download enrollment reports, training records, account balance, and more.
SCORM-compliant courses:Courses can be delivered directly to most corporate Learning Management Systems (LMS).
Purchase orders (POs):POs are accepted from all companies. Request an invoice when starting the procurement process.
Reimbursement:Some employers may reimburse their employees for training expenses. Check your company's policy.
Financial assistance:Payment plans are available to those who qualify. Alternatively, purchasing individual courses one at a time is also an option.
Career advancement:Professional certifications help demonstrate interest and dedication to career and job performance. They may be helpful for those seeking to grow their career or transitioning to a different position within an organization. Professional certifications are a great addition to a resume, offer talking points for the interview, and practical knowledge for performing duties.

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