Introduction to Biopharma: Methods
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2024 UPDATE:
This program is currently unavailable for enrollment.
It may have been updated or discontinued.
Check for newer version in our catalog.
This program is currently unavailable for enrollment.
It may have been updated or discontinued.
Check for newer version in our catalog.
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Free Trial CoursesOutline:INTRODUCTION 1. Course Information 2. Interface Tour 3. Course Overview THE GENOME 4. Objectives 5. Chromosomal Structure 6. DNA Structure 7. Pharmacogenomics 8. Progress Check GENOMICS APPLICATIONS 9. Objectives 10. Applications of the HGI 11. Proteomics 12. Gene Therapy Targets 13. Bioinformatics 14. Progress Check GENOMICS-BASED DRUG DISCOVERY 15. Objectives 16. Drug Targets 17. Medicinal Chemistry 18. Combinatorial Chemistry 19. High-Throughput Screening 20. Progress Check CONCLUSION 21. Summary | Objectives:Specify the structure of human chromatin at five different levels of resolution. Describe the structure of DNA. Define what a SNP is. Explain the fundamental principle of pharmacogenomics. List four ways in which genomics information is used to generate new therapeutic agents. Explain the types of information that proteomics will generate. List three gene therapy approaches that utilize novel genes to target diseases. Understand the concept of bioinformatics. List four different types of cellular drug targets. Define the two technologies that allow the creation of large combinatorial libraries. Specify two of the features of an assay that make it amenable to high-throughput screening. Understand how the combination of high throughput screening and combinatorial chemistry has accelerated drug discovery. | |
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